Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622757 | 0.85 | RECQL (0.36) | RECQLSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15316356 | 0.76 | RECQL (0.47) | RECQLRAB9AMAPTCYP2C19KMT2A | |
| SCHEMBL9708902 | 0.75 | MGLL (0.36) | SMN1; SMN2MAPTKMT2AMGLLPOLB | |
| SCHEMBL21936822 | 0.74 | RECQL (0.35) | RECQLCYP2C19KMT2AMEN1NNMT | |
| SCHEMBL12500156 | 0.73 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL8335906 | 0.73 | ITGB1 (0.43) | SMN1; SMN2NPC1RAB9AMAPTCYP2C19 | |
| SCHEMBL4758814 | 0.73 | HDAC1 (0.45) | NPC1RAB9AMAPTL3MBTL1KMT2A | |
| SCHEMBL7745228 | 0.72 | GAA (0.47) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL15882986 | 0.71 | MGLL (0.35) | SMN1; SMN2KMT2AMGLLPOLB | |
| SCHEMBL11040225 | 0.71 | KDM4E (0.33) | NPC1RAB9AMAPTL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005047840-A | NEW NICOTINIC ACID DERIVATIVE AND METHOD FOR SYNTHESIZING THE SAME | SHIMADZU CORP | 2005-02-24 | — | — | JP | disclosed |