Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867866 | 0.84 | ALDH1A1 (0.45) | GAAHSD17B10CA12CA1CA9 | |
| SCHEMBL6512762 | 0.81 | ALDH1A1 (0.46) | GAAHSD17B10CA12CA1CA9 | |
| SCHEMBL13404894 | 0.79 | CA12 (0.42) | GAAHSD17B10CA12CA1CA9 | |
| SCHEMBL27717830 | 0.79 | CA1 (0.55) | GAAALOX15CA12CA1CA9 | |
| SCHEMBL12756281 | 0.78 | MAPK1 (0.35) | GAAHSD17B10CA12CA1CA9 | |
| SCHEMBL8335906 | 0.78 | ITGB1 (0.43) | GAAESR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26730046 | 0.78 | KMT2A (0.38) | GAAALOX15HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL26729992 | 0.76 | LMNA (0.37) | GAAESR1CA12CA1CA9 | |
| SCHEMBL28736317 | 0.76 | CA1 (0.47) | GAAHSD17B10CA12CA1CA9 | |
| SCHEMBL7129080 | 0.75 | ESR1 (0.44) | GAAESR1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040116-A4 | FUNCTIONALIZED PYRIMIDINE DERIVATIVES | SCRIPPS RESEARCH INST (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6175001-B1 | DERIVATIZED AT C5 TO CONTAIN FUNCTIONAL GROUP THAT MIMICS THE PROPERTY OF NATURALLY OCCURRING AMINO ACID; FOR USE IN POLYMERASE CHAIN REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2001-01-16 | — | — | US | disclosed |
| EP-1040116-A1 | FUNCTIONALIZED PYRIMIDINE DERIVATIVES | The Scripps Research Institute (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-2000052192-A1 | ENZYMATIC DNA MOLECULES THAT CONTAIN MODIFIED NUCLEOTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-09-08 | — | — | WO | disclosed |
| US-6110462-A | NUCLEOTIDE CATALYSTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-08-29 | — | — | US | disclosed |
| WO-2000023456-A1 | FUNCTIONALIZED PYRIMIDINE DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-04-27 | — | — | WO | disclosed |