Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.48 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627106 | 0.80 | FYN (0.44) | FYNHASPIN | |
| SCHEMBL627849 | 0.80 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL627017 | 0.80 | FYN (0.47) | FYNHASPIN | |
| SCHEMBL627536 | 0.78 | FYN (0.37) | FYNHASPINNPY5RPDE10A | |
| SCHEMBL627537 | 0.78 | FYN (0.37) | FYNHASPINNPY5RPDE10A | |
| SCHEMBL628243 | 0.78 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL627385 | 0.77 | NPY5R (0.39) | FYNHASPINNPY5RPDE10A | |
| SCHEMBL625117 | 0.75 | FYN (0.42) | FYNHASPINMKNK1 | |
| SCHEMBL2257059 | 0.67 | MKNK1 (0.63) | FYNHASPINMKNK1 | |
| SCHEMBL628252 | 0.65 | MKNK1 (0.57) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |