Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628243 | 0.84 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL627849 | 0.83 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL627199 | 0.78 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL625461 | 0.77 | FYN (0.33) | FYN | |
| SCHEMBL625118 | 0.76 | POLB (0.31) | — | |
| SCHEMBL627018 | 0.76 | FYN (0.47) | FYNHASPIN | |
| SCHEMBL627017 | 0.76 | FYN (0.47) | FYNHASPIN | |
| SCHEMBL627384 | 0.75 | FYN (0.48) | FYNHASPINMKNK1 | |
| SCHEMBL625467 | 0.74 | PIK3CA (0.48) | FYNHASPIN | |
| SCHEMBL627167 | 0.73 | FYN (0.46) | FYNHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |