Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421175 | 0.81 | — | — | |
| SCHEMBL1553372 | 0.81 | — | — | |
| Water SCHEMBL11361709 | 0.78 | — | — | |
| SCHEMBL1905741 | 0.75 | — | — | |
| SCHEMBL22986023 | 0.67 | — | — | |
| SCHEMBL4531401 | 0.66 | — | — | |
| SCHEMBL346322 | 0.66 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM3CHRM1 | |
| SCHEMBL5530117 | 0.65 | — | — | |
| SCHEMBL904784 | 0.64 | — | — | |
| SCHEMBL15518874 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494989-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084916-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2003-10-16 | — | — | WO | disclosed |