Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300124 | 0.89 | MAPT (0.47) | MAPTCYP2D6CYP2C19CYP2C9ALOX15 | |
| SCHEMBL14193387 | 0.88 | BHMT (0.37) | MAPTCYP2D6CYP2C19CYP2C9ALOX15 | |
| SCHEMBL1176235 | 0.83 | ALOX15 (0.48) | CYP2D6CYP2C19CYP2C9ALOX15NOD1 | |
| SCHEMBL10660324 | 0.82 | CYP2D6 (0.40) | MAPTCYP2D6CYP2C19CYP2C9ALOX15 | |
| SCHEMBL8285850 | 0.82 | CYP2D6 (0.40) | MAPTCYP2D6CYP2C19CYP2C9ALOX15 | |
| SCHEMBL13662314 | 0.82 | P2RY10 (0.36) | MAPTKMT2A | |
| SCHEMBL27686000 | 0.82 | P2RY10 (0.36) | MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL1176232 | 0.81 | ALOX15 (0.46) | CYP2D6CYP2C19CYP2C9ALOX15NOD1 | |
| Hydrochloric Acid SCHEMBL7001552 | 0.81 | ALOX15 (0.46) | CYP2D6CYP2C19CYP2C9ALOX15NOD1 | |
| SCHEMBL7337554 | 0.79 | MAPT (0.44) | MAPTCYP2D6CYP2C19CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603558-A1 | PROCESS FOR PREPARATION OF PERINDOPRIL AND SALTS THEREOF | Lupin Limited (IN) | 2005-12-14 | — | — | EP | claimed |
| WO-2004075889-A1 | PROCESS FOR PREPARATION OF PERINDOPRIL AND SALTS THEREOF | LUPIN LIMITED (IN) | 2004-09-10 | — | — | WO | claimed |