Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173430 | 0.97 | TSHR (0.39) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL17105916 | 0.94 | TSHR (0.44) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL869304 | 0.94 | TSHR (0.44) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL27630454 | 0.94 | TSHR (0.44) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL17105915 | 0.94 | TSHR (0.44) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL771775 | 0.94 | TSHR (0.44) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL804367 | 0.92 | TSHR (0.42) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL15497547 | 0.90 | TSHR (0.40) | TSHRTHRBLMNASLC22A1 | |
| SCHEMBL11200 | 0.88 | TSHR (0.35) | TSHRTHRBLMNA | |
| SCHEMBL787078 | 0.86 | TSHR (0.35) | TSHRTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402840-A1 | HEAT CURABLE ELASTOMER COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017123925-A1 | HEAT CURABLE ELASTOMER COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |
| EP-1536765-A1 | AQUEOUS EMULSION COMPRISING AN ORGANOSILICON POLYMER | Dow Corning Toray Silicone Company, Ltd. (JP) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004024117-A1 | AQUEOUS EMULSION COMPRISING AN ORGANOSILICON POLYMER | DOW CORNING TORAY SILICONE CO.,LTD. (JP) | 2004-03-25 | — | — | WO | disclosed |