Sugi Predict

Sugi Predict / Compounds / SCHEMBL173430

SCHEMBL173430

SCHEMBL173430

CCCCC[Si](C)(C)O[Si](C)(C)CCCCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.39
▸ THRB P10828 1/20 0.39
▸ LMNA P02545 4/20 0.33
▸ SLC22A1 O15245 3/20 0.32
▸ SLC22A2 O15244 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ DNM1 Q05193 5/20 0.30
▸ ALDH1A1 P00352 3/20 0.30
▸ MEN1 O00255 2/20 0.30
▸ KMT2A Q03164 2/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27630454 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL17105916 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL869304 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL17105915 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL771775 0.97 TSHR (0.44) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL6274075 0.97 TSHR (0.37) TSHRTHRBLMNASLC22A1SLC22A2
SCHEMBL804367 0.95 TSHR (0.42) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL15497547 0.92 TSHR (0.40) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL11200 0.91 TSHR (0.35) TSHRTHRBLMNA
SCHEMBL787078 0.89 TSHR (0.35) TSHRTHRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 — — US claimed
EP-3558222-B1 WATER-IN-OIL EMULSION COMPRISING A PARTICULAR EMULSIFYING SYSTEM, A LIPOPHILIC CLAY, AND AN ORGANOPOLYSILOXANE ELASTOMER POWDER COATED WITH A SILICONE RESIN OREAL (FR) 2024-04-03 — — EP disclosed
EP-3558238-B1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL OREAL (FR) 2023-08-23 — — EP disclosed
US-20230126240-A1 COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-04-27 — — US disclosed
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt L'OREAL (FR) 2022-07-05 — — US disclosed
CN-110099662-B Water-in-oil emulsion comprising a specific emulsifying system, a lipophilic clay and a silicone resin-coated organopolysiloxane elastomer powder 莱雅公司 2022-04-26 — — CN disclosed
US-20210048392-A1 FLUORESCENCE-BASED DETECTION OF PROTEIN AGGREGATION AND FIBER OPTIC-BASED BENCHTOP INSTRUMENT MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-02-18 — — US disclosed
WO-2021030378-A1 FLUORESCENCE-BASED DETECTION OF PROTEIN AGGREGATION AND FIBER OPTIC-BASED BENCHTOP INSTRUMENT MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-02-18 — — WO disclosed
US-20200338068-A1 PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF a,ß-UNSATURATED KETONE COMPOUNDS SpecGx LLC (US) 2020-10-29 — — US disclosed
EP-3558216-B1 WATER-IN-OIL EMULSION CONTAINING BAICALIN, A XANTHINE BASE, A VITAMIN B3, AND A POLYVALENT METAL CATION SALT L'ORÉAL (FR) 2020-09-16 — — EP disclosed
US-5338872-A Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof FLORIDA STATE UNIVERSITY (US) 1994-08-16 — — US disclosed
WO-1994017050-A1 C7 TAXANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FLORIDA STATE UNIVERSITY (US) 1994-08-04 — — WO disclosed
WO-1994017051-A1 PROCESS FOR THE PREPARATION OF BACCATIN III ANALOGS BEARING NEW C2 AND C4 FUNCTIONAL GROUPS FLORIDA STATE UNIVERSITY (US) 1994-08-04 — — WO disclosed
WO-1994017052-A1 C2 TAXANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FLORIDA STATE UNIVERSITY (US) 1994-08-04 — — WO disclosed
WO-1994015929-A1 PROCESS FOR THE PREPARATION OF 10-DESACETOXYBACCATIN III FLORIDA STATE UNIVERSITY (US) 1994-07-21 — — WO disclosed
WO-1994015599-A1 C10 TAXANE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FLORIDA STATE UNIVERSITY (US) 1994-07-21 — — WO disclosed
EP-0642503-A4 10-DESACETOXYTAXOL DERIVATIVES. UNIV FLORIDA STATE (US) 1994-07-07 — — EP disclosed
WO-1994010996-A1 BUTENYL-SUBSTITUTED TAXANES AND COMPOSITION FLORIDA STATE UNIVERSITY (US) 1994-05-26 — — WO disclosed
WO-1994010997-A1 TAXANES HAVING AN ALKYL SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FLORIDA STATE UNIVERSITY (US) 1994-05-26 — — WO disclosed
WO-1993006093-A1 10-DESACETOXYTAXOL DERIVATIVES FLORIDA STATE UNIVERSITY (US) 1993-04-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt KRT18, BROX, S100B TSHR 4866/4885THRB 2270/4885LMNA 1468/4885
US-20200338068-A1 PROCESSES FOR PREPARING MORPHINAN-6-ONE PRODUCTS WITH LOW LEVELS OF a,ß-UNSATURATED KETONE COMPOUNDS FASN, CYP1B1, CLN6 TSHR 4717/4885THRB 3166/4885LMNA 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.