Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272935 | 0.94 | EPHX1 (0.44) | EPHX1TRPM8POLB | |
| SCHEMBL6762833 | 0.94 | EPHX1 (0.44) | EPHX1TRPM8POLB | |
| SCHEMBL6710245 | 0.94 | EPHX1 (0.44) | EPHX1TRPM8POLB | |
| SCHEMBL6268429 | 0.83 | EPHX1 (0.41) | EPHX1TRPM8POLB | |
| SCHEMBL3336695 | 0.79 | EPHX1 (0.42) | EPHX1TRPM8 | |
| SCHEMBL6274682 | 0.79 | EPHX1 (0.42) | EPHX1TRPM8 | |
| SCHEMBL6268386 | 0.77 | EPHX1 (0.53) | EPHX1 | |
| SCHEMBL6275638 | 0.74 | EPHX1 (0.55) | EPHX1 | |
| SCHEMBL6274792 | 0.73 | AAK1 (0.40) | EPHX1 | |
| SCHEMBL6271399 | 0.72 | PLG (0.39) | EPHX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |