Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271761 | 0.93 | KMT2A (0.41) | PLGKMT2APSMB5POLBOPRM1 | |
| SCHEMBL6274839 | 0.84 | EPHX1 (0.47) | PLGPLATLMNAPSMB5SMN1; SMN2 | |
| SCHEMBL1651189 | 0.80 | HSD11B1 (0.43) | KMT2APSMB5POLBOPRM1SMN1; SMN2 | |
| SCHEMBL6274792 | 0.78 | AAK1 (0.40) | PSMB5SMN1; SMN2HSD17B10ANPEPEPHX1 | |
| SCHEMBL6274117 | 0.76 | EPHX1 (0.53) | KMT2APSMB5SMN1; SMN2HSD17B10EPHX1 | |
| SCHEMBL26583876 | 0.76 | EPHX1 (0.48) | KMT2APSMB5SMN1; SMN2HSD17B10EPHX1 | |
| SCHEMBL6267439 | 0.76 | ROCK2 (0.45) | LMNAKMT2APSMB5POLBSMN1; SMN2 | |
| SCHEMBL265529 | 0.75 | LMNA (0.48) | PLGPLATLMNASMN1; SMN2ANPEP | |
| SCHEMBL135660 | 0.75 | LMNA (0.48) | PLGPLATLMNASMN1; SMN2ANPEP | |
| SCHEMBL135662 | 0.75 | LMNA (0.48) | PLGPLATLMNASMN1; SMN2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |