Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270878 | 0.92 | ALOX5 (0.43) | LMNATDP1ALOX5ROCK2ROCK1 | |
| SCHEMBL659048 | 0.92 | ALOX5 (0.43) | LMNATDP1ALOX5ROCK2ROCK1 | |
| SCHEMBL8073959 | 0.92 | ALOX5 (0.43) | LMNATDP1ALOX5ROCK2ROCK1 | |
| SCHEMBL1692318 | 0.89 | ROCK2 (0.43) | LMNAPLGPLATTDP1ALOX5 | |
| SCHEMBL824154 | 0.89 | ROCK2 (0.43) | LMNAPLGPLATTDP1ALOX5 | |
| SCHEMBL10270877 | 0.89 | ROCK2 (0.43) | LMNAPLGPLATTDP1ALOX5 | |
| SCHEMBL28283154 | 0.87 | ROCK2 (0.42) | LMNAPLGPLATTDP1ALOX5 | |
| Hydrochloric Acid SCHEMBL1692314 | 0.87 | ROCK2 (0.42) | LMNAPLGPLATTDP1ALOX5 | |
| Hydrochloric Acid SCHEMBL1692312 | 0.87 | ROCK2 (0.42) | LMNAPLGPLATTDP1ALOX5 | |
| SCHEMBL28284574 | 0.85 | ROCK2 (0.41) | LMNAPLGPLATTDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |