Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695374 | 0.92 | ALOX5 (0.43) | ALDH1A1FFAR4ALOX5 | |
| SCHEMBL19545606 | 0.82 | FFAR4 (0.36) | FFAR4 | |
| SCHEMBL3152751 | 0.79 | — | — | |
| SCHEMBL10098974 | 0.79 | — | — | |
| SCHEMBL6274757 | 0.76 | FFAR4 (0.35) | FFAR4 | |
| SCHEMBL10073917 | 0.75 | SPHK1 (0.36) | ALDH1A1 | |
| SCHEMBL28747541 | 0.74 | GRM2 (0.55) | — | |
| SCHEMBL28023532 | 0.74 | ALOX5 (0.41) | ALDH1A1FFAR4ALOX5 | |
| SCHEMBL16506470 | 0.74 | — | — | |
| SCHEMBL29188019 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592661-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004065361-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-05 | — | — | WO | disclosed |