Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073918 | 0.94 | SPHK1 (0.39) | SPHK1CPB2GPR119ALDH1A1 | |
| SCHEMBL30158917 | 0.84 | CYP4F2 (0.41) | SPHK1CPB2GPR119 | |
| SCHEMBL29187860 | 0.84 | CYP4F2 (0.41) | SPHK1CPB2GPR119 | |
| SCHEMBL29187859 | 0.84 | CYP4F2 (0.41) | SPHK1CPB2GPR119 | |
| SCHEMBL30159122 | 0.83 | ALOX5 (0.33) | CPB2ALDH1A1KMT2A | |
| SCHEMBL12033287 | 0.83 | NR1H2 (0.33) | SPHK1KMT2A | |
| SCHEMBL13330148 | 0.83 | NR1H2 (0.33) | SPHK1KMT2A | |
| SCHEMBL13123340 | 0.83 | NR1H2 (0.33) | SPHK1KMT2A | |
| SCHEMBL29188005 | 0.80 | NR1H2 (0.39) | KMT2A | |
| SCHEMBL29188007 | 0.80 | NR1H2 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | NATIONAL SCIENCE FOUNDATION | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | PPOX, POR, PCCA | SPHK1 3516/4885CPB2 632/4885GPR119 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.