Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270872 | 0.81 | ALDH1A1 (0.46) | ALOX5MGLLHTR2AHTR2CHTR2B | |
| SCHEMBL1827924 | 0.78 | HTT (0.51) | ALOX5CYP1A2HTR3EHTR3BTHRB | |
| SCHEMBL16296350 | 0.70 | ALOX5 (0.47) | ALOX5MGLLCYP1A2CYP2C19HTR3E | |
| SCHEMBL6272012 | 0.69 | S100A9 (0.40) | NOTUM | |
| SCHEMBL6273466 | 0.69 | DAO (0.49) | CYP2C19CYP2C9HTR2CMAPTHPGD | |
| SCHEMBL2963118 | 0.67 | MAPT (0.44) | CYP1A2CYP2C9HTTMAPTGAA | |
| SCHEMBL10948802 | 0.66 | MEN1 (0.49) | ALOX5MGLLCYP1A2CYP2C19HTR3E | |
| SCHEMBL9623886 | 0.65 | ALDH1A1 (0.71) | ALOX5MGLLCYP1A2CYP2C19HTR3E | |
| SCHEMBL2541490 | 0.65 | IDO1 (0.60) | MGLLCYP1A2CYP2C19HTR3EHTR3B | |
| SCHEMBL3013325 | 0.64 | GAA (0.59) | ALOX5MGLLCYP1A2CYP2C19HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008055-A1 | NOVEL TETRAZOLONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014198592-A1 | NOVEL TETRAZOLONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-12-18 | — | — | WO | disclosed |
| EP-1606271-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080984-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | WO | disclosed |