Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 14/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274260 | 0.87 | VCAM1 (0.41) | VCAM1GPR55HPNMAPTALOX15 | |
| SCHEMBL6274329 | 0.87 | VCAM1 (0.41) | VCAM1GPR55HPNMAPTALOX15 | |
| SCHEMBL6275098 | 0.87 | NPSR1 (0.46) | VCAM1 | |
| SCHEMBL6270647 | 0.84 | VCAM1 (0.41) | VCAM1 | |
| SCHEMBL6288160 | 0.84 | VCAM1 (0.44) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6249029 | 0.82 | VCAM1 (0.61) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6274597 | 0.82 | VCAM1 (0.45) | VCAM1ALOX15 | |
| Camobucol SCHEMBL4734553 | 0.80 | VCAM1 (0.70) | VCAM1GPR55CD69ELANEHPN | |
| SCHEMBL6276412 | 0.80 | VCAM1 (0.37) | VCAM1HPNMAPTALOX15SIRT5 | |
| SCHEMBL6290031 | 0.78 | ALOX15 (0.38) | VCAM1HPNMAPTALOX15SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005112914-A2 | PHENOLIC ANTIOXIDANTS FOR THE TREATMENT OF DISORDERS INCLUDING ARTHRITIS, ASTHMA AND CORONARY ARTERY DISEASE | ATHEROGENICS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |