Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.64 |
| ▸ | ATIC | P31939 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275454 | 1.00 | RPS6KA3 (0.64) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| SCHEMBL5356833 | 0.84 | RPS6KA3 (0.61) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| SCHEMBL8947084 | 0.83 | POLB (0.66) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| SCHEMBL6125745 | 0.83 | POLB (0.66) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| Resorcin Brown SCHEMBL31650975 | 0.82 | RPS6KA3 (0.59) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| Resorcin Brown SCHEMBL110507 | 0.82 | RPS6KA3 (0.59) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| Resorcin Brown SCHEMBL110506 | 0.82 | RPS6KA3 (0.59) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| Resorcin Brown SCHEMBL185546 | 0.81 | RPS6KA3 (0.57) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| Resorcin Brown SCHEMBL185544 | 0.81 | RPS6KA3 (0.57) | RPS6KA3ATICCYP1A2CYP2C9GLO1 | |
| SCHEMBL9711553 | 0.79 | RPS6KA3 (1.00) | RPS6KA3ATICCYP1A2CYP2C9GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005314228-A | TRANILAST-CONTAINING MEDICINE COMPOSITION IN PACKAGE | ROHTO PHARMACEUT CO LTD | 2005-11-10 | — | — | JP | disclosed |
| JP-2005314229-A | TRANILAST-CONTAINING MEDICINE COMPOSITION | ROHTO PHARMACEUT CO LTD | 2005-11-10 | — | — | JP | disclosed |