Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcin Brown SCHEMBL31650975 | 1.00 | RPS6KA3 (0.59) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| Resorcin Brown SCHEMBL110506 | 1.00 | RPS6KA3 (0.59) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| Resorcin Brown SCHEMBL185546 | 0.99 | RPS6KA3 (0.57) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| Resorcin Brown SCHEMBL185544 | 0.99 | RPS6KA3 (0.57) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| Resorcin Brown SCHEMBL185545 | 0.89 | THRB (0.53) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| Resorcin Brown SCHEMBL109260 | 0.89 | THRB (0.53) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL8946891 | 0.87 | NPC1 (0.61) | ALDH1A1HIF1ACYP1A2CYP2C9NPC1 | |
| SCHEMBL5351766 | 0.86 | RPS6KA3 (0.59) | RPS6KA3ALDH1A1HIF1ACYP1A2CYP2C9 | |
| SCHEMBL19958473 | 0.84 | NPC1 (0.69) | ALDH1A1HIF1ACYP1A2NPC1RAB9A | |
| SCHEMBL1567479 | 0.83 | FTO (0.61) | ALDH1A1HIF1ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968534-B2 | Anionic direct dye having a tetraalkylammonium counterion, dyeing composition comprising them and method for dyeing keratinous fibres starting from these dyes | L'OREAL (FR) | 2018-05-15 | — | — | US | disclosed |
| EP-2424491-B1 | FILM FORMER IN HAIR COLOURS | HENKEL AG & CO KGAA (DE) | 2017-05-24 | — | — | EP | disclosed |
| EP-2802383-A2 | USE OF PROPYLENE OXIDE-MODIFIED STARCH FOR IMPROVING ARTIFICIAL COLOURING OF KERATIN FIBRES | Henkel AG&Co. KGAA (DE) | 2014-11-19 | — | — | EP | disclosed |
| US-20130227797-A1 | ANIONIC DIRECT DYE HAVING A TETRAALKYLAMMONIUM COUNTERION, DYEING COMPOSITION COMPRISING THEM AND METHOD FOR DYEING KERATINOUS FIBRES STARTING FROM THESE DYES | L'OREAL (FR) | 2013-09-05 | — | — | US | disclosed |
| WO-2013087296-A2 | COMPOSITIONS FOR COLOURING KERATIN FIBRES | HENKEL AG & CO. KGAA (DE) | 2013-06-20 | — | — | WO | disclosed |
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| EP-1697006-B2 | USE OF PEPTIDES TO PROTECT SKIN FROM HAIR TREATMENT AGENTS | WELLA AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |
| EP-2211994-A2 | OXIDATIVE DYEING METHOD FOR KERATINOUS FIBERS | Henkel AG & Co. KGaA (DE) | 2010-08-04 | — | — | EP | disclosed |
| EP-2192957-A1 | BRIGHTENING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND HYDROGEN PEROXIDE | Henkel AG & Co. KGaA (DE) | 2010-06-09 | — | — | EP | disclosed |
| EP-0863739-B1 | HAIR DYE | WELLA AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| US-20020000012-A1 | Compositions and methods for dyeing keratin fibers, especially hair | WELLA AKTIENGESELLSCHAFT (DE) | 2002-01-03 | — | — | US | disclosed |
| US-5972044-A | Composition and method for dyeing keratin fibers | WELLA AG (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5865853-A | Composition for dyeing keratin fibers containing vegetable dyes, a direct dye compound and oil and method of dyeing hair using same | WELLA AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
| EP-0888768-A2 | Hair-dye | Wella Aktiengesellschaft (DE) | 1999-01-07 | — | — | EP | disclosed |
| EP-0867170-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | disclosed |
| EP-0857476-A1 | Use of tanning agents to extend the shelf life of hair dyes | Wella Aktiengesellschaft (DE) | 1998-08-12 | — | — | EP | disclosed |
| EP-0852942-A1 | Composition for dyeing and tinting hair | Wella Aktiengesellschaft (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0821935-A2 | Composition for dyeing and tinting hair | Wella Aktiengesellschaft (DE) | 1998-02-04 | — | — | EP | disclosed |
| EP-0806199-A2 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1997-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020000012-A1 | Compositions and methods for dyeing keratin fibers, especially hair | KRT18, DSG1, KRTCAP2 | RPS6KA3 3976/4885ALDH1A1 426/4885HIF1A 4137/4885 |
| US-20130227797-A1 | ANIONIC DIRECT DYE HAVING A TETRAALKYLAMMONIUM COUNTERION, DYEING COMPOSITION COMPRISING THEM AND METHOD FOR DYEING KERATINOUS FIBRES STARTING FROM THESE DYES | KRT18, COL1A1, COL14A1 | RPS6KA3 3682/4885ALDH1A1 639/4885HIF1A 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.