SCHEMBL8947084

SCHEMBL8947084

O=S(=O)(O)c1ccc(/N=N/c2ccc(O)c(/N=N/c3ccccc3)c2O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.66
▸ CYP2D6 P10635 1/20 0.66
▸ RPS6KA3 P51812 1/20 0.59
▸ ATIC P31939 1/20 0.55
▸ GLO1 Q04760 1/20 0.54
▸ PHLPP2 Q6ZVD8 3/20 0.49
▸ KMT2A Q03164 4/20 0.49
▸ MAPT P10636 3/20 0.49
▸ GAA P10253 2/20 0.49
▸ MAPK1 P28482 2/20 0.49
▸ TDP1 Q9NUW8 2/20 0.49
▸ MEN1 O00255 3/20 0.49
▸ CYP1A2 P05177 3/20 0.48
▸ CYP2C9 P11712 2/20 0.48
▸ CYP2C19 P33261 2/20 0.46
▸ TSHR P16473 1/20 0.46
▸ PTPRA P18433 1/20 0.46
▸ PTPRB P23467 1/20 0.46
▸ HIF1A Q16665 1/20 0.46
▸ RAPGEF4 Q8WZA2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6125745 1.00 POLB (0.66) POLBCYP2D6RPS6KA3ATICGLO1
SCHEMBL6813525 0.86 THRB (0.56) GLO1KMT2AMAPTGAAMAPK1
SCHEMBL29411151 0.86 THRB (0.56) GLO1KMT2AMAPTGAAMAPK1
SCHEMBL9475617 0.86 THRB (0.56) GLO1KMT2AMAPTGAAMAPK1
SCHEMBL6275449 0.83 RPS6KA3 (0.64) POLBCYP2D6RPS6KA3ATICGLO1
SCHEMBL6275454 0.83 RPS6KA3 (0.64) POLBCYP2D6RPS6KA3ATICGLO1
Resorcin Brown SCHEMBL31650975 0.82 RPS6KA3 (0.59) POLBCYP2D6RPS6KA3ATICGLO1
Resorcin Brown SCHEMBL110507 0.82 RPS6KA3 (0.59) POLBCYP2D6RPS6KA3ATICGLO1
Resorcin Brown SCHEMBL110506 0.82 RPS6KA3 (0.59) POLBCYP2D6RPS6KA3ATICGLO1
SCHEMBL408153 0.81 POLB (1.00) POLBCYP2D6RPS6KA3ATICGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 — — US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 — — US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 — — US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 — — US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 — — US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 — — US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 — — US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 — — US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 — — US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 — — US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 — — US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 — — US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 — — US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 — — US disclosed
US-8579428-B2 Colorants XEROX CORPORATION (US) 2013-11-12 — — US disclosed
US-20130184388-A1 Colorants XEROX CORPORATION (US) 2013-07-18 — — US disclosed
US-8444715-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2013-05-21 — — US disclosed
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2012-11-01 — — US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 — — US disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885CYP2D6 1888/4885RPS6KA3 4726/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885CYP2D6 1888/4885RPS6KA3 4726/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885CYP2D6 1888/4885RPS6KA3 4726/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885CYP2D6 1888/4885RPS6KA3 4726/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885CYP2D6 1888/4885RPS6KA3 4726/4885
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 POLB 683/4885CYP2D6 1888/4885RPS6KA3 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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