Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161093 | 0.98 | SMN1; SMN2 (0.50) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8830679 | 0.95 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7872778 | 0.95 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7870895 | 0.95 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10893740 | 0.95 | LMNA (0.59) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Ethylene Glycol SCHEMBL23391388 | 0.91 | LMNA (0.48) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL1705524 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| Ethylene Glycol SCHEMBL23391398 | 0.91 | LMNA (0.48) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7863756 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL7875788 | 0.91 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180303846-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES | NYU WINTHROP HOSPITAL (US) | 2018-10-25 | — | — | US | disclosed |
| US-20160375034-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES | MICROBION CORPORATION | 2016-12-29 | — | — | US | disclosed |
| US-9028878-B2 | Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses | MICROBION CORPORATION (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130058983-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES | MICROBION CORPORATION | 2013-03-07 | — | — | US | disclosed |
| CN-102083408-A | Cosmetic compositions comprising exopolysaccharides derived from microbial mats, and use thereof | INNOVACTIV INC | 2011-06-01 | — | — | CN | disclosed |
| US-20050282755-A1 | Compositions having antimicrobial activity and uses thereof | ANSATA THERAPEUTICS, INC. (US) | 2005-12-22 | — | — | US | disclosed |
| WO-2005090385-A2 | COMPOSITIONS HAVING ANTIMICROBIAL ACTIVITY AND USES THEREOF | ANSATA THERAPEUTICS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180303846-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES | TST, BTD, BTF3 | LMNA 4868/4885ALDH1A1 3269/4885MEN1 1986/4885 |
| US-20160375034-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES | TST, BTD, BTF3 | LMNA 4868/4885ALDH1A1 3269/4885MEN1 1986/4885 |
| US-20130058983-A1 | BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES | TST, BTD, BTF3 | LMNA 4868/4885ALDH1A1 3269/4885MEN1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.