Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994492 | 0.86 | RAB9A (0.47) | RAB9AHSD11B1MEN1KMT2ABDKRB1 | |
| SCHEMBL4027806 | 0.82 | SLC22A12 (0.42) | RAB9AHSD11B1MEN1KMT2ABDKRB1 | |
| SCHEMBL27642658 | 0.80 | MEN1 (0.51) | RAB9AHSD11B1MEN1KMT2ASLC22A12 | |
| SCHEMBL11888733 | 0.79 | RAB9A (0.62) | RAB9AHSD11B1MEN1KMT2ABDKRB1 | |
| Hydrochloric Acid SCHEMBL28351640 | 0.78 | MEN1 (0.50) | RAB9AHSD11B1MEN1KMT2ASLC22A12 | |
| SCHEMBL3996842 | 0.77 | CNR2 (0.47) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL4476644 | 0.77 | BDKRB1 (0.56) | RAB9AHSD11B1MEN1KMT2ABDKRB1 | |
| SCHEMBL5216082 | 0.77 | BDKRB1 (0.43) | RAB9AHSD11B1MEN1KMT2ABDKRB1 | |
| SCHEMBL18672669 | 0.74 | HSD17B10 (0.42) | RAB9AHSD11B1MEN1KMT2ABDKRB1 | |
| SCHEMBL17300857 | 0.74 | TDP1 (0.39) | HSD11B1MEN1KMT2ABDKRB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606288-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087700-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2004-10-14 | — | — | WO | disclosed |