Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994492 | 0.79 | RAB9A (0.47) | BDKRB1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL4894694 | 0.78 | LMNA (0.53) | KMT2ASMN1; SMN2MEN1POLBLMNA | |
| SCHEMBL6276147 | 0.77 | RAB9A (0.45) | BDKRB1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL11888733 | 0.75 | RAB9A (0.62) | BDKRB1RAB9AKMT2AMEN1POLB | |
| SCHEMBL5218879 | 0.74 | VCAM1 (0.48) | KMT2ASMN1; SMN2MEN1POLBLMNA | |
| SCHEMBL4891235 | 0.74 | LMNA (0.41) | KMT2ASMN1; SMN2POLBLMNAALDH1A1 | |
| SCHEMBL4476644 | 0.73 | BDKRB1 (0.56) | BDKRB1RAB9AKMT2AMEN1POLB | |
| SCHEMBL4027806 | 0.73 | SLC22A12 (0.42) | BDKRB1RAB9AKMT2AMEN1HSD11B1 | |
| SCHEMBL5209884 | 0.72 | LMNA (0.46) | KMT2ASMN1; SMN2MEN1POLBLMNA | |
| SCHEMBL27642658 | 0.70 | MEN1 (0.51) | RAB9AKMT2ASMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812405-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048209-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |