Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488996 | 0.84 | HTR2C (0.40) | HTR2CL3MBTL1ADORA2AADORA1 | |
| SCHEMBL2494591 | 0.67 | CFTR (0.58) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6276429 | 0.67 | EPHB4 (0.50) | AURKAL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3751857 | 0.66 | CFTR (0.56) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL5477688 | 0.65 | NUDT1 (0.55) | HTR2CL3MBTL1ADORA2AADORA1 | |
| SCHEMBL103894 | 0.65 | HTR2C (0.53) | AURKAHTR2CL3MBTL1ADORA2AADORA1 | |
| SCHEMBL6730606 | 0.64 | CFTR (0.46) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL5474686 | 0.64 | AURKA (0.50) | AURKASMN1; SMN2 | |
| SCHEMBL20385475 | 0.64 | SLC6A2 (0.42) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL24621170 | 0.63 | CFTR (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005085252-A1 | IMIDAZO ‘1,2-A’ PYRAZINE COMPOUNDS WHICH INTERACT WITH PROTEIN KINASES | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-09-15 | — | — | WO | disclosed |