Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716594 | 0.81 | CPB2 (0.46) | CPB2GSRRNPEPCYP1A2EPOR | |
| SCHEMBL9716597 | 0.81 | CPB2 (0.46) | CPB2GSRRNPEPCYP1A2EPOR | |
| SCHEMBL6279174 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL9716651 | 0.76 | CYP1A2 (0.42) | CPB2GSRRNPEPCYP1A2EPOR | |
| SCHEMBL9716642 | 0.76 | CYP1A2 (0.42) | CPB2GSRRNPEPCYP1A2EPOR | |
| SCHEMBL29832367 | 0.73 | CPB2 (0.43) | CPB2GSR | |
| SCHEMBL29832205 | 0.73 | CPB2 (0.43) | CPB2GSR | |
| Lysine SCHEMBL16879782 | 0.70 | GSR (0.67) | CPB2GSRRNPEPCYP1A2ALDH1A1 | |
| SCHEMBL787391 | 0.69 | GSR (0.46) | CPB2GSRRNPEPEPORFOLH1 | |
| SCHEMBL9716771 | 0.69 | GSR (0.46) | CPB2GSRRNPEPEPORFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379547-B1 | MODIFIED CYCLOSPORIN AS A PRO-DRUG AND USE THEREOF AS A MEDICAMENT | DEBIOPHARM SA (CH) | 2005-12-21 | — | — | EP | disclosed |