Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.54 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.54 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.54 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.54 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.54 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.54 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.54 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.54 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.54 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.54 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277116 | 1.00 | ALOX15 (0.54) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6276850 | 0.95 | ALOX15 (0.53) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6276857 | 0.95 | ALOX15 (0.53) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8490417 | 0.93 | ALOX15 (0.62) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6274277 | 0.92 | MGAM (0.56) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6274270 | 0.92 | MGAM (0.56) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6276971 | 0.91 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL6274707 | 0.91 | MAOB (0.53) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6274714 | 0.91 | MAOB (0.53) | ALOX15TDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8488507 | 0.90 | ALOX15 (0.58) | ALOX15TDP1CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1273578-B1 | Benzopyran derivatives and antiallergic agent containing the same | DAINIPPON INK & CHEMICALS (JP) | 2005-02-23 | — | — | EP | disclosed |
| US-6670391-B2 | For inhibiting both immediate and delayed type allergic reactions; side effect reduction | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-12-30 | — | — | US | disclosed |
| US-20030096860-A1 | Benzopyran derivative and antiallergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-05-22 | — | — | US | disclosed |
| EP-1273578-A1 | Benzopyran derivatives and antiallergic agent containing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096860-A1 | Benzopyran derivative and antiallergic agent | HRH2, HRH1, HRH4 | ALOX15 416/4885TDP1 2417/4885CYP3A4 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.