Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669146 | 1.00 | CETP (0.43) | CETPIDO1TDO2PPARGFFAR1 | |
| SCHEMBL1899039 | 0.92 | PDE2A (0.42) | CETPPPARGFFAR1CASRPDE2A | |
| SCHEMBL5669024 | 0.92 | PDE2A (0.42) | CETPPPARGFFAR1CASRPDE2A | |
| SCHEMBL6568878 | 0.92 | IDO1 (0.43) | CETPIDO1TDO2 | |
| SCHEMBL6566052 | 0.92 | IDO1 (0.43) | CETPIDO1TDO2 | |
| SCHEMBL6064713 | 0.91 | CETP (0.40) | CETPIDO1TDO2 | |
| SCHEMBL6435008 | 0.91 | CETP (0.40) | CETPIDO1TDO2 | |
| SCHEMBL5671099 | 0.90 | CETP (0.42) | CETPIDO1TDO2KCNH2 | |
| SCHEMBL1899658 | 0.90 | CETP (0.42) | CETPIDO1TDO2KCNH2 | |
| SCHEMBL5670878 | 0.90 | CETP (0.42) | CETPIDO1TDO2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005117869-A1 | COMBINATIONS COMPRISING (S)-AMLODIPINE AND A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR, AND METHODS FOR REDUCING HYPERTENSION | SEPRACOR INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-1401399-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES | Pfizer Products Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003000226-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |