Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 12/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064713 | 1.00 | CETP (0.40) | CETPIDO1TDO2ADRB2ADRB1 | |
| SCHEMBL6571229 | 0.95 | CETP (0.41) | CETPIDO1TDO2LMNA | |
| SCHEMBL6565905 | 0.95 | CETP (0.41) | CETPIDO1TDO2LMNA | |
| SCHEMBL1899658 | 0.93 | CETP (0.42) | CETPIDO1TDO2 | |
| SCHEMBL5671099 | 0.93 | CETP (0.42) | CETPIDO1TDO2 | |
| SCHEMBL6430199 | 0.92 | CETP (0.40) | CETPADRB2ADRB1SMN1; SMN2LMNA | |
| SCHEMBL6273236 | 0.92 | CETP (0.40) | CETPADRB2ADRB1SMN1; SMN2LMNA | |
| SCHEMBL6277313 | 0.91 | CETP (0.43) | CETPIDO1TDO2 | |
| SCHEMBL5669146 | 0.91 | CETP (0.43) | CETPIDO1TDO2 | |
| SCHEMBL6566052 | 0.91 | IDO1 (0.43) | CETPIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578415-A1 | DOSAGE FORMS COMPRISING A CETP INHIBITOR AND AN HMG-COA REDUCTASE INHIBITOR | Pfizer Products Inc. (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004056358-A1 | DOSAGE FORMS COMPRISING A CETP INHIBITOR AND AN HMG-COA REDUCTASE INHIBITOR | PFIZER PRODUCTS INC. (US) | 2004-07-08 | — | — | WO | disclosed |