SCHEMBL6566052

SCHEMBL6566052

OC(CNC(c1cccc(Oc2ccccc2)c1)c1cc(C(F)(F)F)ccc1F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
CETP P11597 14/20 0.40
MAPK14 Q16539 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568878 1.00 IDO1 (0.43) IDO1TDO2CETPMAPK14
SCHEMBL5671186 0.94 CETP (0.41) IDO1TDO2CETPMAPK14
SCHEMBL1565225 0.94 CETP (0.41) IDO1TDO2CETPMAPK14
SCHEMBL5671099 0.92 CETP (0.42) IDO1TDO2CETPMAPK14
SCHEMBL1899658 0.92 CETP (0.42) IDO1TDO2CETPMAPK14
SCHEMBL6277313 0.92 CETP (0.43) IDO1TDO2CETP
SCHEMBL5669146 0.92 CETP (0.43) IDO1TDO2CETP
SCHEMBL5668949 0.92 CETP (0.40) CETPMAPK14
SCHEMBL6569007 0.92 CETP (0.40) CETPMAPK14
SCHEMBL6435008 0.91 CETP (0.40) IDO1TDO2CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401399-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES Pfizer Products Inc. (US) 2004-03-31 EP disclosed
WO-2003000226-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed