Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277693 | 0.85 | MAPK1 (0.57) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL9451313 | 0.84 | MAPK1 (0.55) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL1729519 | 0.82 | MAPK1 (0.75) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL3071450 | 0.78 | CA12 (0.56) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL10597796 | 0.77 | MAPK1 (0.68) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL3920395 | 0.77 | MAPK1 (0.68) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL10186609 | 0.77 | MAPK1 (0.68) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| 1-Methoxy-3-Propoxybenzene SCHEMBL791921 | 0.77 | MAPK1 (0.62) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL5038332 | 0.76 | MAPK1 (0.62) | MAPK1MTNR1AMTNR1BALDH1A1TSHR | |
| 1-Butyloxy-3-Methoxybenzene SCHEMBL1071738 | 0.75 | MAPK1 (0.61) | MAPK1MTNR1AMTNR1BALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048916-A2 | TETRAHYDROSPIRO-BETA-CARBOLINE-1,3 '-PYRROLIDINE DERIVATIVES AND THEIR USE IN GHSR-RELATED DISORDERS | BIOVITRUM AB (SE) | 2005-06-02 | — | — | WO | disclosed |