Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16047480 | 0.90 | HDAC1 (0.34) | MMETSHRALDH1A1KMT2AMAPT | |
| SCHEMBL17668001 | 0.85 | MME (0.36) | MMETSHRALDH1A1KMT2AMAPT | |
| SCHEMBL26122506 | 0.81 | MME (0.45) | MMEALDH1A1PKM | |
| SCHEMBL29141153 | 0.81 | ELANE (0.32) | ALDH1A1ELANEPKM | |
| SCHEMBL44725 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30367749 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5485914 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL16047481 | 0.72 | HDAC1 (0.36) | ALDH1A1HDAC1HDAC2HDAC4HDAC6 | |
| SCHEMBL29427565 | 0.72 | HDAC1 (0.34) | MT-CO2ALOX5HDAC1HDAC2HDAC4 | |
| SCHEMBL28279888 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180223260-A1 | FUNCTIONALIZED NANOPARTICLES FOR THE INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES AND METHODS FOR THEIR MANUFACTURE AND USE | STEMGENICS, INC. (US) | 2018-08-09 | — | — | US | claimed |
| US-20180223260-A1 | FUNCTIONALIZED NANOPARTICLES FOR THE INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES AND METHODS FOR THEIR MANUFACTURE AND USE | STEMGENICS, INC. (US) | 2018-08-09 | — | — | US | disclosed |
| EP-0941738-B1 | Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria | WYETH CORP (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20040052804-A1 | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria | WYETH HOLDINGS CORPORATION | 2004-03-18 | — | — | US | disclosed |
| US-6645503-B1 | Eliciting a cross reactive immune response against heterologous strains of the gram negative bacteria; vaccines; comprises the inner core and lipid A portions of the lipopolysaccharide | WYETH HOLDINGS CORPORATION | 2003-11-11 | — | — | US | disclosed |
| EP-0941738-A1 | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria | American Cyanamid Company (US) | 1999-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040052804-A1 | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria | LY96, DDOST, LRBA | MME 1023/4885TSHR 3105/4885ALDH1A1 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.