Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 16/20 | 0.62 |
| ▸ | IDO1 | P14902 | 15/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22699080 | 0.74 | TDO2 (0.72) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22698971 | 0.72 | TDO2 (1.00) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22699001 | 0.72 | TDO2 (0.79) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL628393 | 0.72 | CASP3 (0.53) | HTTSMN1; SMN2TOP2A | |
| SCHEMBL22698975 | 0.71 | TDO2 (0.81) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22698982 | 0.71 | TDO2 (0.78) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22698996 | 0.70 | TDO2 (1.00) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22699022 | 0.70 | TDO2 (1.00) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22699007 | 0.70 | TDO2 (0.74) | TDO2IDO1HPGDMAPK1HTT | |
| SCHEMBL22699004 | 0.70 | TDO2 (0.73) | TDO2IDO1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021409-A3 | Anthraquinone Analogs | UTAH STATE UNIVERSITY (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012021409-A2 | Anthraquinone Analogs | UTAH STATE UNIVERSITY (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021409-A2 | Anthraquinone Analogs | UTAH STATE UNIVERSITY (US) | 2012-02-16 | — | — | WO | disclosed |