Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 3/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062525 | 0.95 | LSS (0.59) | LSSSTAT3ALDH1A1KDM4EMAPK8 | |
| SCHEMBL1063883 | 0.90 | L3MBTL1 (0.56) | TDP1L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL1062764 | 0.85 | LSS (0.59) | LSSL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL22516948 | 0.84 | LSS (0.78) | LSSALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL1063461 | 0.83 | MEN1 (0.49) | LSSL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL1063797 | 0.82 | LMNA (0.55) | L3MBTL1ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL1063679 | 0.81 | GPR183 (0.57) | LSSL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL1064485 | 0.80 | SMN1; SMN2 (0.61) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL1059658 | 0.78 | MAPK14 (0.58) | LSSL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL1063340 | 0.78 | MAPK14 (0.49) | L3MBTL1ALDH1A1KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110455-A2 | COMBINATION THERAPY FOR TREATING HEPATITIS VIRUS INFECTION | INTERMUNE, INC. (US) | 2005-11-24 | — | — | WO | disclosed |