Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GCK | P35557 | 5/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228854 | 0.82 | MEN1 (0.60) | NPSR1MEN1KMT2AFFAR4SCN9A | |
| SCHEMBL564521 | 0.79 | ALDH1A1 (0.60) | NPSR1MEN1KMT2AKDM1AMAOA | |
| SCHEMBL3847455 | 0.78 | KMT2A (0.52) | NPSR1MEN1KMT2ASCN9AALOX12 | |
| SCHEMBL5911665 | 0.78 | KDM1A (0.68) | MEN1KMT2AKDM1AMAOAALDH1A1 | |
| SCHEMBL5911698 | 0.78 | KMT2A (0.62) | NPSR1MEN1KMT2ASCN9AALOX12 | |
| SCHEMBL30209696 | 0.76 | MEN1 (0.67) | NPSR1MEN1KMT2ASCN9AKDM1A | |
| SCHEMBL6253625 | 0.72 | ALDH1A1 (0.63) | KMT2AFFAR1FFAR4SCN9AALDH1A1 | |
| SCHEMBL31596007 | 0.72 | FFAR1 (0.76) | MEN1KMT2AFFAR1FFAR4ALDH1A1 | |
| SCHEMBL29471301 | 0.72 | ALDH1A1 (0.75) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27650147 | 0.72 | KMT2A (1.00) | MEN1KMT2AALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |