Tetrahydrofuran

Tetrahydrofuran

SCHEMBL6278435

C1CCOC1.OCC1CO1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
PDK1 Q15118 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycidol SCHEMBL9717914 0.97 ALDH1A1 (0.40) ALDH1A1PDK1TDP1TSHR
Tetrahydrofuran SCHEMBL29105255 0.97 ALDH1A1 (0.40) ALDH1A1PDK1TDP1TSHR
Glycidol SCHEMBL29249394 0.97 ALDH1A1 (0.40) ALDH1A1PDK1TDP1TSHR
Glycidol SCHEMBL7938201 0.86
SCHEMBL1395058 0.85 PDK1 (0.39) ALDH1A1PDK1
SCHEMBL2846269 0.83 PDK1 (0.38) ALDH1A1PDK1
Cyclohexane SCHEMBL29194299 0.83 ALDH1A1 (0.40) ALDH1A1PDK1TDP1TSHR
Glycidol SCHEMBL8375576 0.83 ALDH1A1 (0.44) ALDH1A1PDK1TDP1TSHR
Glycidol SCHEMBL2014115 0.83 ALDH1A1 (0.44) ALDH1A1PDK1TDP1TSHR
Glycidol SCHEMBL377563 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325066-A Aprotic thermosensitive polymer and synthetic method and application thereof 华南理工大学 2024-07-12 CN disclosed
CN-109843936-A Polymeric compositions prepare its method and the product comprising it 马萨诸塞大学 2019-06-04 CN disclosed
EP-1162243-B1 UV curable composition SICPA HOLDING SA (CH) 2005-08-03 EP disclosed
US-20030134939-A1 Forming a scratch-off layer on a substrate to temporarily hide information; epoxy compound; nucleophilic compounds that crosslinks with the epoxide; photoinitiator UBS AG (CH) 2003-07-17 US disclosed
WO-2001094483-A1 UV CURABLE COMPOSITION SICPA HOLDING S.A. (CH) 2001-12-13 WO disclosed
EP-1162243-A1 UV curable composition Sicpa Holding S.A. (CH) 2001-12-12 EP disclosed
US-6319428-B1 Perfluorinated amide salts and their uses as ionic conducting materials HYDRO-QUEBEC (CA) 2001-11-20 US disclosed