Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278644 | 1.00 | TSHR (0.35) | TSHRCYP3A4PPARAKDM4EPPARG | |
| SCHEMBL6363693 | 0.89 | TSHR (0.33) | TSHRCYP3A4PPARAKDM4ERXRA | |
| SCHEMBL6363697 | 0.89 | TSHR (0.33) | TSHRCYP3A4PPARAKDM4ERXRA | |
| SCHEMBL6282950 | 0.82 | LMNA (0.33) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL6279817 | 0.82 | HNF4A (0.33) | TSHRCYP3A4PPARAKDM4EPPARG | |
| SCHEMBL6282953 | 0.82 | LMNA (0.33) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL6279811 | 0.82 | HNF4A (0.33) | TSHRCYP3A4PPARAKDM4EPPARG | |
| SCHEMBL6278754 | 0.82 | TSHR (0.36) | TSHRCYP3A4PPARAKDM4EPPARG | |
| SCHEMBL6284731 | 0.80 | PPARA (0.35) | TSHRCYP3A4PPARAKDM4EPPARG | |
| SCHEMBL6284722 | 0.80 | PPARA (0.35) | TSHRCYP3A4PPARAKDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |