Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 12/20 | 0.88 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282683 | 0.94 | SOAT1 (1.00) | SOAT1POLBLMNATHRBSHMT2 | |
| SCHEMBL8157356 | 0.89 | SOAT1 (0.91) | SOAT1POLBLMNATHRBSHMT2 | |
| SCHEMBL6282168 | 0.89 | SOAT1 (0.81) | SOAT1POLBLMNATHRBSHMT2 | |
| Hydrochloric Acid SCHEMBL6282102 | 0.85 | SOAT1 (0.78) | SOAT1POLBLMNATHRBSHMT2 | |
| SCHEMBL6280710 | 0.83 | SOAT1 (0.80) | SOAT1POLBLMNATHRBSHMT2 | |
| Hydrochloric Acid SCHEMBL6280620 | 0.83 | SOAT1 (0.79) | SOAT1POLBLMNATHRBSHMT2 | |
| SCHEMBL4513200 | 0.82 | SOAT1 (1.00) | SOAT1POLB | |
| SCHEMBL4526190 | 0.79 | SOAT1 (0.68) | SOAT1POLBLMNATHRBSHMT2 | |
| SCHEMBL6286120 | 0.79 | SOAT1 (1.00) | SOAT1POLB | |
| SCHEMBL6280750 | 0.78 | SOAT1 (1.00) | SOAT1POLBLMNASHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969711-B2 | Cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | KOWA COMPANY, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038987-A1 | Novel cyclic diamine compounds and medicine containing the same | LCAT, ACAT2, ACAT1 | SOAT1 5/4885POLB 1313/4885LMNA 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.