Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702494 | 0.91 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL6274384 | 0.80 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL13547708 | 0.78 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL6278534 | 0.78 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL6279104 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL6274361 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL1702962 | 0.77 | ALDH1A1 (0.66) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL13547675 | 0.75 | ALDH1A1 (0.76) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL24209696 | 0.75 | NPSR1 (0.67) | L3MBTL1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6278157 | 0.74 | KMT2A (0.66) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005115147-A2 | HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2005-12-08 | — | — | WO | disclosed |