SCHEMBL627990

SCHEMBL627990

O=CN1c2ccccc2Sc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.52
BCHE P06276 13/20 0.52
ACHE P22303 4/20 0.48
NOX1 Q9Y5S8 1/20 0.48
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13938144 0.84 BCHE (0.54) BCHEACHEMEN1LMNAKMT2A
SCHEMBL10889466 0.80 CYP2D6 (0.50) MAOABCHEACHENOX1LMNA
SCHEMBL23753204 0.80 NOX1 (0.41) MAOABCHEACHENOX1MEN1
SCHEMBL1001931 0.80 HDAC1 (0.45) MAOABCHEACHENOX1
SCHEMBL9184458 0.79 MAPT (0.41) BCHEACHENOX1LMNA
SCHEMBL9186707 0.79 MAPT (0.39) MAOABCHEACHENOX1LMNA
SCHEMBL9185325 0.79 MAPT (0.39) MAOABCHEACHENOX1LMNA
SCHEMBL9185337 0.78 MAPT (0.40) BCHEACHENOX1LMNA
SCHEMBL272974 0.77 MAOA (0.52) MAOABCHEACHENOX1MEN1
SCHEMBL9077377 0.77 MAOA (0.52) MAOABCHEACHENOX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1883987-A1 SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL 3M Innovative Properties Company (US) 2008-02-06 EP claimed
US-20060263697-A1 Substituted phenothiazine redox shuttles for rechargeable lithium-ion cell 3M INNOVATIVE PROPERTIES COMPANY 2006-11-23 US claimed
WO-2006124738-A1 SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-11-23 WO claimed
WO-2001092240-A1 NOVEL N-SUBSTITUTED PHENOTHIAZINES AND THEIR USE AS MODULATORS OF SERINE HYDROLASE ENZYMES DALHOUSIE UNIVERSITY (CA) 2001-12-06 WO claimed
EP-0451675-B1 Process for the direct and regioselective functionalization in position 2 of phenothiazine ZAMBON SPA (IT) 1995-11-02 EP claimed
US-5109134-A PROCESS FOR THE DIRECT AND REGIOSELECTIVE FUNCTIONALIZATION IN POSITION 2 OF PHENOTHIAZINE ZAMBON GROUP S.P.A. (IT) 1992-04-28 US claimed
US-5089613-A Sulfonation of N-acylphenothiazine with sulfuric acid, oleum or chlorosulfonic acid then reduciton to mercaptan and S-alkylation ZAMBON GROUP S.P.A. (IT) 1992-02-18 US claimed
EP-0451675-A1 Process for the direct and regioselective functionalization in position 2 of phenothiazine ZAMBON GROUP S.p.A. (IT) 1991-10-16 EP claimed
EP-0433841-A2 Process for the direct and regioselective functionalization in position 2 of phenotiazine ZAMBON GROUP S.p.A. (IT) 1991-06-26 EP claimed
CN-115611787-A Organic luminescent material with double fluorescence emission characteristics and preparation method and application thereof 杭州师范大学 2023-01-17 CN disclosed
CN-115010619-A Organic luminescent material and application thereof 南京邮电大学 2022-09-06 CN disclosed
CN-103172591-B Phenothiazinyl-containing Schiff base compound as well as preparation method and application thereof UNIV SHAANXI SCIENCE & TECH 2014-07-30 CN disclosed
CN-102197010-B Process for producing p-dichlorobenzene TOSOH CORP 2013-12-04 CN disclosed
CN-103172591-A Phenothiazinyl-containing Schiff base compound as well as preparation method and application thereof UNIV SHAANXI SCIENCE & TECH 2013-06-26 CN disclosed
US-5089613-A Sulfonation of N-acylphenothiazine with sulfuric acid, oleum or chlorosulfonic acid then reduciton to mercaptan and S-alkylation ZAMBON GROUP S.P.A. (IT) 1992-02-18 US disclosed
EP-0451675-A1 Process for the direct and regioselective functionalization in position 2 of phenothiazine ZAMBON GROUP S.p.A. (IT) 1991-10-16 EP disclosed
EP-0433841-A2 Process for the direct and regioselective functionalization in position 2 of phenotiazine ZAMBON GROUP S.p.A. (IT) 1991-06-26 EP disclosed
US-4766125-A N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia JANSSEN PHARMACEUTICA N.V. (BE) 1988-08-23 US disclosed
US-4571437-A CATALYTIC HYDROGENATION REDUCTION AND REARRANGEMENT OF NITROBENZENE IN PRESENCE OF SULFUR COMPOUND MALLINCKRODT, INC. (US) 1986-02-18 US disclosed
EP-0068544-A2 Novel N-aryl-piperazinealkanamides JANSSEN PHARMACEUTICA N.V. (BE) 1983-01-05 EP disclosed