Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918841 | 0.75 | SMN1; SMN2 (0.50) | ITGB3ITGA2BALDH1A1MAPTHSD17B10 | |
| SCHEMBL6703929 | 0.75 | SMN1; SMN2 (0.50) | ITGB3ITGA2BALDH1A1MAPTHSD17B10 | |
| SCHEMBL28860254 | 0.74 | SMN1; SMN2 (0.46) | ITGB3ALDH1A1KMT2A | |
| SCHEMBL6173007 | 0.74 | SMN1; SMN2 (0.46) | ITGB3ITGA2BALDH1A1MAPTHSD17B10 | |
| SCHEMBL13707538 | 0.73 | NAPRT (0.35) | ITGB3ITGA2BNAPRTL3MBTL1ALDH1A1 | |
| SCHEMBL1981859 | 0.73 | ACE (0.43) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1981363 | 0.73 | ACE (0.43) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1981863 | 0.73 | ACE (0.43) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL742952 | 0.70 | ITGB3 (0.60) | ITGB3ITGA2BHSD17B10CHKAKDM4E | |
| SCHEMBL29514498 | 0.69 | NOTUM (0.51) | ITGB3ITGA2BHSD17B10CHKALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005132746-A | PYRIDYLPYRROLIDINEDICARBOXAMIDE DERIVATIVE | TOKUYAMA CORP | 2005-05-26 | — | — | JP | disclosed |