SCHEMBL6280042

SCHEMBL6280042

C=Cc1ccccc1CCc1cccc(C)c1C=C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 3/20 0.34
TSHR P16473 2/20 0.34
PTGER4 P35408 2/20 0.33
PTGER3 P43115 2/20 0.33
PTGER2 P43116 2/20 0.33
GPR84 Q9NQS5 1/20 0.32
CDK4 P11802 1/20 0.32
CCND1 P24385 1/20 0.32
MAPT P10636 1/20 0.32
PTGER1 P34995 1/20 0.31
MITF O75030 1/20 0.31
KMT2A Q03164 1/20 0.31
DAO P14920 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6284367 0.89 TAAR1 (0.39) TAAR1ALDH1A1TSHRGPR84MAPT
SCHEMBL28399661 0.85 TAAR1 (0.50) TAAR1ALDH1A1TSHRGPR84CDK4
SCHEMBL29377653 0.81 ALDH1A1 (0.48) TAAR1ALDH1A1TSHRMAPTMITF
SCHEMBL595200 0.81 ALDH1A1 (0.48) TAAR1ALDH1A1TSHRMAPTMITF
SCHEMBL6280044 0.80 ALDH1A1 (0.38) TAAR1ALDH1A1MITFKMT2A
SCHEMBL5072509 0.79 ALDH1A1 (0.46) TAAR1ALDH1A1TSHRMAPTMITF
SCHEMBL27286804 0.79 CYP3A4 (0.38) TAAR1TSHR
SCHEMBL7921184 0.77 ALDH1A1 (0.41) ALDH1A1TSHRMAPTACHE
SCHEMBL78218 0.77 ALDH1A1 (0.41) ALDH1A1TSHRMITF
SCHEMBL2775950 0.77 GABRA1 (0.43) TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6855952-B2 Semiconductor device and semiconductor package HITACHI, LTD. (JP) 2005-02-15 US disclosed
US-20040038021-A1 Semiconductor device and semiconductor package HITACHI, LTD. (JP) 2004-02-26 US disclosed