Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | PROC | P04070 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414236 | 0.85 | F10 (0.40) | F10F2PRSS1PLGPROC | |
| SCHEMBL7413979 | 0.85 | TSHR (0.33) | F10F2PRSS1 | |
| SCHEMBL6275854 | 0.82 | F10 (0.49) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6275985 | 0.80 | F10 (0.42) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7413647 | 0.80 | F10 (0.42) | F10F2PRSS1PLGPROC | |
| SCHEMBL7411753 | 0.79 | F2 (0.33) | F10F2PRSS1PLGPROC | |
| SCHEMBL6280998 | 0.78 | F10 (0.48) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6283322 | 0.78 | HDAC6 (0.34) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7410177 | 0.71 | F10 (0.41) | F10F2PRSS1PLGPROC | |
| SCHEMBL7516860 | 0.71 | F10 (0.42) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |