Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 5/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.33 |
| ▸ | PLG | P00747 | 3/20 | 0.32 |
| ▸ | PROC | P04070 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275985 | 0.83 | F10 (0.42) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6279410 | 0.83 | F10 (0.49) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7414989 | 0.81 | F10 (0.46) | F10F2PRSS1PLGPROC | |
| SCHEMBL7411273 | 0.80 | F10 (0.33) | F10F2PRSS1PLGPROC | |
| SCHEMBL6280043 | 0.78 | HDAC6 (0.36) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7403888 | 0.78 | F10 (0.42) | F10F2PRSS1PLGPROC | |
| SCHEMBL7407161 | 0.74 | F10 (0.48) | F10F2PRSS1PLGPROC | |
| SCHEMBL6284137 | 0.74 | F10 (0.50) | F10F2PRSS1PLGPROC | |
| SCHEMBL7414004 | 0.74 | F10 (0.34) | HDAC6HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7410237 | 0.74 | F10 (0.40) | F10F2PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |