Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 16/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | PROC | P04070 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413979 | 0.87 | TSHR (0.33) | F2F10PRSS1GSK3B | |
| SCHEMBL7414265 | 0.85 | F10 (0.34) | F2F10PRSS1CACNA1SPLG | |
| SCHEMBL7413647 | 0.85 | F10 (0.42) | F2F10PRSS1PLGPROC | |
| SCHEMBL7408084 | 0.84 | F10 (0.34) | F2F10PRSS1CACNA1SPLG | |
| SCHEMBL7412228 | 0.83 | CACNA1S (0.33) | F10CACNA1S | |
| SCHEMBL7115736 | 0.82 | F10 (0.49) | F2F10PRSS1CACNA1SPLG | |
| SCHEMBL7412407 | 0.79 | F10 (0.35) | F2F10PRSS1GSK3BCACNA1S | |
| SCHEMBL7414236 | 0.79 | F10 (0.40) | F2F10PRSS1PLGPROC | |
| SCHEMBL6280043 | 0.79 | HDAC6 (0.36) | F2F10PRSS1PLGPROC | |
| SCHEMBL7413490 | 0.79 | TSHR (0.33) | F2F10PRSS1PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068191-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999050257-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |