Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280250 | 1.00 | MAPT (0.52) | MAPTRXFP1CYSLTR2CYSLTR1PTGER4 | |
| SCHEMBL6001910 | 0.89 | PPARG (0.53) | CYSLTR2CYSLTR1S1PR1S1PR3TRPA1 | |
| SCHEMBL4510771 | 0.81 | FFAR1 (0.43) | MAPTRXFP1CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL4510764 | 0.81 | FFAR1 (0.43) | MAPTRXFP1CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL9518443 | 0.81 | PPARG (0.55) | CYSLTR2CYSLTR1LTB4R2 | |
| SCHEMBL9518451 | 0.81 | PPARG (0.55) | CYSLTR2CYSLTR1LTB4R2 | |
| SCHEMBL7013170 | 0.81 | FFAR1 (0.45) | MAPTRXFP1CYSLTR2CYSLTR1LTB4R | |
| SCHEMBL9521115 | 0.77 | PPARG (0.53) | MAPTCYSLTR2CYSLTR1LTB4R2 | |
| SCHEMBL9469166 | 0.77 | PPARG (0.53) | MAPTCYSLTR2CYSLTR1LTB4R2 | |
| SCHEMBL9469170 | 0.77 | PPARG (0.53) | MAPTCYSLTR2CYSLTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |