Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280250 | 0.89 | MAPT (0.52) | S1PR1CYSLTR2CYSLTR1S1PR3TRPA1 | |
| SCHEMBL6280253 | 0.89 | MAPT (0.52) | S1PR1CYSLTR2CYSLTR1S1PR3TRPA1 | |
| SCHEMBL6002329 | 0.84 | ALOX5 (0.53) | PPARGS1PR1CYSLTR2CYSLTR1FAAH | |
| SCHEMBL7625428 | 0.84 | ALOX5 (0.53) | PPARGS1PR1CYSLTR2CYSLTR1FAAH | |
| SCHEMBL6000349 | 0.82 | FAAH (0.43) | PPARGPPARAS1PR1FAAHPDE4A | |
| SCHEMBL6000368 | 0.80 | PPARG (0.54) | PPARGPPARACYSLTR2CYSLTR1FAAH | |
| SCHEMBL9469067 | 0.79 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL9469070 | 0.79 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL9469066 | 0.79 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL11723240 | 0.78 | PPARG (0.51) | PPARGPPARACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-1216222-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019776-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |