Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | RELA | Q04206 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980444 | 0.81 | RELA (0.44) | FAAHRELATSHRMEN1ALDH1A1 | |
| SCHEMBL10481393 | 0.79 | FAAH (0.38) | FAAHRELATSHRMEN1ALDH1A1 | |
| SCHEMBL4565920 | 0.77 | FAAH (0.50) | FAAHRELACA2 | |
| SCHEMBL28075544 | 0.76 | FAAH (0.46) | FAAHRELAMEN1ALDH1A1LMNA | |
| SCHEMBL461711 | 0.76 | RELA (0.46) | FAAHRELATSHRALDH1A1CA2 | |
| SCHEMBL8518454 | 0.73 | FAAH (0.50) | FAAHTSHRALDH1A1MAPT | |
| SCHEMBL9851083 | 0.72 | RELA (0.39) | FAAHRELAMEN1ALDH1A1LMNA | |
| SCHEMBL8679501 | 0.72 | FAAH (0.38) | FAAHRELATSHRMEN1ALDH1A1 | |
| SCHEMBL1325482 | 0.71 | CA12 (0.31) | CA2 | |
| SCHEMBL11755607 | 0.71 | FAAH (0.45) | FAAHRELAMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |