Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.64 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MPI | P34949 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978711 | 0.87 | GAA (0.65) | PDE7APDE7BCA12CA9MEN1 | |
| SCHEMBL30103233 | 0.79 | PDE7A (1.00) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL844588 | 0.79 | PDE7A (1.00) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL6283951 | 0.79 | PDE7A (0.71) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL6306891 | 0.79 | PDE7A (0.71) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL6276511 | 0.77 | PDE7A (0.68) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL6279687 | 0.76 | PDE7A (0.66) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL6283903 | 0.74 | PDE7A (0.63) | PDE7APDE7BCA12CA1CA2 | |
| SCHEMBL6982431 | 0.72 | TP53 (0.57) | PDE7APDE7BCA12CA9MEN1 | |
| SCHEMBL10889569 | 0.72 | PDE4A (0.57) | MEN1KMT2AALDH1A1MPIAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897213-B1 | Heterocycles as cholecystokinin (CCK) ligands | WARNER-LAMBERT COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| WO-1996020178-A1 | NOVEL HETEROCYCLES AS CHOLECYSTOKININ (CCK) LIGANDS | WARNER-LAMBERT COMPANY (US) | 1996-07-04 | — | — | WO | disclosed |