Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084617 | 0.83 | NAAA (0.65) | NAAAALDH1A1GAATSHRASAH1 | |
| SCHEMBL4074285 | 0.83 | NAAA (0.65) | NAAAALDH1A1GAATSHRASAH1 | |
| SCHEMBL3734489 | 0.83 | NAAA (0.65) | NAAAALDH1A1GAATSHRASAH1 | |
| SCHEMBL6579209 | 0.81 | BDKRB1 (0.44) | NAAAOPRK1OPRD1 | |
| SCHEMBL13934739 | 0.81 | IDO1 (0.50) | ALDH1A1GAATSHRIDO1TDO2 | |
| SCHEMBL1872257 | 0.80 | BDKRB1 (0.46) | OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL1873147 | 0.78 | BDKRB1 (0.45) | OPRK1OPRD1 | |
| SCHEMBL4118291 | 0.78 | KCNQ2 (0.48) | NAAAALDH1A1GAATSHRIDO1 | |
| SCHEMBL6279081 | 0.78 | KCNQ2 (0.48) | NAAAALDH1A1GAATSHRIDO1 | |
| SCHEMBL5504422 | 0.78 | KCNQ2 (0.48) | NAAAALDH1A1GAATSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556047-A2 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004032848-A2 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |