Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383709 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL2381110 | 0.88 | MAPK1 (0.43) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL2382552 | 0.88 | ALDH1A1 (0.41) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL3867849 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL2383613 | 0.86 | ALDH1A1 (0.41) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL3444475 | 0.85 | ACHE (0.46) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL3445384 | 0.84 | ACHE (0.45) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL5738768 | 0.83 | KDM4E (0.37) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL2383356 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL2385374 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1MEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556382-A1 | 3-PHENYL SUBSTITUTED PYRIDOINDOLONE, PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004041817-A1 | 3-PHENYL SUBSTITUTED PYRIDOINDOLONE, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2004-05-21 | — | — | WO | disclosed |