SCHEMBL6281163

SCHEMBL6281163

C=Cc1ccc(C(O)OC(=O)Oc2ccc(C=CC=Cc3ccc(OC(C)OCC)cc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
PTGS2 P35354 1/20 0.37
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
LTB4R Q15722 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33
ACACB O00763 1/20 0.32
MAOB P27338 4/20 0.32
KDM4E B2RXH2 3/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
TTR P02766 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6279159 0.89 BCHE (0.35) BCHEACHEPTGS2TAS1R3TAS1R1
SCHEMBL6279120 0.87 BCHE (0.37) BCHEACHEPTGS2TAS1R3TAS1R1
SCHEMBL6427959 0.85 PTGS2 (0.38) BCHEACHEPTGS2TAS1R3TAS1R1
SCHEMBL6843705 0.81 ELANE (0.38) BCHEMAOBSLC5A1SLC5A2ABCG2
SCHEMBL6279560 0.80 BCHE (0.36) BCHEACHEPTGS2TAS1R3TAS1R1
SCHEMBL6279349 0.79 BCHE (0.35) BCHEACHEPTGS2LTB4RLTB4R2
SCHEMBL7271956 0.79 SMN1; SMN2 (0.32) TAS1R3TAS1R1LTB4RLTB4R2KDM4E
SCHEMBL4968186 0.79 PTGS2 (0.36) BCHEACHEPTGS2TAS1R3TAS1R1
SCHEMBL6275962 0.79 BCHE (0.35) BCHEACHEPTGS2TAS1R3TAS1R1
SCHEMBL6279132 0.78 CHRNB2 (0.34) BCHEACHEPTGS2LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0875787-B1 Method for reducing the substrate dependence of resist WAKO PURE CHEM IND LTD (JP) 2005-12-14 EP disclosed
EP-0789279-B2 Polymer and resist material WAKO PURE CHEM IND LTD (JP) 2004-12-08 EP disclosed
US-6656660-B1 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-02 US disclosed
EP-0780732-B1 Polymer composition and resist material WAKO PURE CHEM IND LTD (JP) 2003-07-09 EP disclosed
US-6303264-B1 PROFILE OF PATTERN OF QUARTER MICRON ORDER WITHOUT CAUSING FOOTING, WHILE RETAINING HIGH RESOLUTION ABILITY AND HIGH SENSITIVITY WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2001-10-16 US disclosed
EP-0789279-B1 Polymer and resist material WAKO PURE CHEM IND LTD (JP) 2001-03-21 EP disclosed
EP-1024406-A1 Resist composition WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 2000-08-02 EP disclosed
US-6033826-A POLYHYDROXYSTYRENE DERIVATIVE CONTAINING AN ACETAL OR KETAL GROUP WHICH CAN EASILY BE ELIMINATED IN THE PRESENCE OF AN ACID IN THE MOLECULE AND HAVING A VERY NARROW MOLECULAR WEIGHT DISTRIBUTION GIVES A RESIST MATERIAL WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-07 US disclosed
US-5976759-A ALKALI SOLUBLE BY HEATING WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-02 US disclosed
EP-0875787-A1 Method for reducing the substrate dependence of resist Wako Pure Chemical Industries, Ltd. (JP) 1998-11-04 EP disclosed
EP-0789279-A1 Polymer and resist material WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1997-08-13 EP disclosed
EP-0780732-A2 Polymer composition and resist material WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1997-06-25 EP disclosed