Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.65 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.65 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.65 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.62 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.62 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970785 | 1.00 | SLC28A1 (0.65) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL1363344 | 0.90 | SLC28A1 (0.66) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL8588528 | 0.86 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4543042 | 0.86 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL1532521 | 0.86 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL8074165 | 0.85 | P2RY6 (0.77) | P2RY6P2RY2P2RY4P2RY14 | |
| SCHEMBL12259056 | 0.85 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL121732 | 0.85 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4849446 | 0.85 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL5612643 | 0.84 | SLC28A1 (0.71) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884881-B1 | 2′-Substituted RNA preparation | AVECIA LIMITED (GB) | 2005-04-26 | — | — | US | disclosed |
| EP-1165584-B1 | 2'-SUBSTITUTED RNA PREPARATION | AVECIA LTD (GB) | 2004-01-21 | — | — | EP | disclosed |
| EP-1165584-A1 | 2'-SUBSTITUTED RNA PREPARATION | Avecia Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056747-A1 | 2'-SUBSTITUTED RNA PREPARATION | AVECIA LIMITED (GB) | 2000-09-28 | — | — | WO | disclosed |